Образование и опыт работы:
2016 – 2021 гг. специалист с отличием, Новосибирский национальный исследовательский государственный университет (НГУ), Новосибирск, Россия.
04.06.2018 – 01.08.2018 в лаборатории Stuart L. Schreiber. Выполнение проекта "Synthesis of the DNA-encoded library scaffolds. Understanding the decarboxylative cross-coupling reactions mechanisms and stereoselectivity". The Scripps Research Institute, Ла-Хойя, Калифорния, США.
01.08.2016 – 18.08.2016 в лаборатории Cristina Pujades. Выполнение проекта "Neurogenesis regulation in the posterior embryonic brain". School of Molecularand Theoretical Biology, Inc., Барселона, Испания.
2019 – 2021 гг. лаборант лаборатории многоспиновых координационных соединений, Международный томографический центр СО РАН (МТЦ СО РАН) , Новосибирск, Россия.
2021 – н.в. аспирантура, Институт органической химии им. Н.Д. Зелинского РАН , Москва, Россия.
Научные интересы:
Медицинская химия, исследования механизмов цитотоксичности, химический синтез, полифторированные соединения, механистические исследования.
Член Российского химического общества им. Д.И. Менделеева c 2017 года.
Публикации:
[1] Kolesnikov, A.E., Egorova, K.S., Ananikov, V.P., 2025. Integrated toxicity assessment of complex chemical mixtures in catalytic reactions. J. Hazard. Mater. 490, 137784. https://doi.org/10.1016/j.jhazmat.2025.137784.
[2] Kolesnikov, A.E., Grebennikov, N.O., Romanenko, K.A., Egorova, K.S., Ananikov, V.P., 2025. Tox-Scapes: A visual and quantitative tool for selecting safer chemical reactions by means of cytotoxicity assessment. J. Clean. Prod. 519, 145970. https://doi.org/10.1016/j.jclepro.2025.145970.
[3] Kolesnikov, A.E., Tikhomirov, A.D., Strukova, E.N., Egorova, K.S., Ananikov, V.P., 2025. Antimicrobial activity / cytotoxicity trade-offs in ionic liquids: Optimizing the balance via structural variations. J. Mol. Liq. 432, 127843. https://doi.org/10.1016/j.molliq.2025.127843.
[4] Egorova, K.S., Kolesnikov, A.E., Tikhomirov, A.D., Filippov, A.A., Ananikov, V.P., 2025. What do we learn when we study cytotoxicity? Critical shortcomings in Green Chemistry context using imidazolium ionic liquids as a case example. Green Chem. 27 (26), 7863-7877. https://doi.org/10.1039/d5gc00836k.
[5] Egorova, K.S., Kolesnikov, A.E., Posvyatenko, A.V., Galushko, A.S., Shaydullin, R.R., Ananikov, V.P., 2024. Establishing the main determinants of the environmental safety of catalytic fine chemical synthesis with catalytic cross-coupling reactions. Green Chem. 26 (5), 2825-2841. https://doi.org/10.1039/d3gc04572b.
[6] Pankov, R., Khanipova, A., Son, A., Prima, D., Kolesnikov, A., Ivanova, N., Fakhrutdinov, A., Minyaev, M., Ananikov, V.P., 2025. Hybrid tuning in NHC ligands: Synergistic effects of BIAN ?-conjugation and aryl ?-modulation in gold(I) complexes. Chem. Eur. J., e202501647. https://doi.org/10.1002/chem.202501647.
[7] Chernavin, P., Letyagin, G., Tolstikov, S., Kolesnikov, A., Romanenko, G., Smirnova, K., Borodulina, A., Ovcharenko, V., Bogomyakov, A., 2024. Pyridyl-substituted nitronyl nitroxides: Comprehensive magnetochemical and quantum chemical study. Chem. Eur. J. 30 (46), e202400873. https://doi.org/10.1002/chem.202400873.
[8] Boichenko, D.S., Kolomoets, N.I., Boiko, D.A., Galushko, A.S., Posvyatenko, A.V., Kolesnikov, A.E., Egorova, K.S., Ananikov, V.P., 2024. Build-a-Bio-Strip: An online platform for rapid toxicity assessment in chemical synthesis. J. Chem. Inf. Model. 64 (22), 8373-8378. https://doi.org/10.1021/acs.jcim.4c01381.
[9] Kolesnikov, A.E., Bryzgalov, A.O., Tolstikov, S.E., Yanshole, V.V., Romanenko, G.V., Letyagin, G.A., Smirnova, K.A., Tolstikova, T.G., Bogomyakov, A.S., Ovcharenko, V.I., 2024. Novel pyridyl-substituted nitronyl nitroxides as potential antiarrhythmic and hypotensive agents with low toxicity and enhanced stability in aqueous solutions. Nitric Oxide 143, 9-15. https://doi.org/10.1016/j.niox.2023.12.001.
[10] Tolstikov, S.E., Kolesnikov, A.E., Smirnova, K.A., Letyagin, G.A., Bogomyakov, A.S., Romanenko, G.V., Ovcharenko, V.I., 2025. Heterospin molecular complexes of Cu(hfac)2 with pyridyl-substituted nitronyl nitroxides: peculiarities of structure and magnetic properties. New J. Chem. 49 (18), 7655-7660. https://doi.org/10.1039/d5nj00967g.
[11] Egorova, K.S., Posvyatenko, A.V., Galushko, A.S., Kolesnikov, A.E., 2024. Comparison of assessments of overall toxicity of chemical reactions upon using cytotoxicity and acute toxicity data. Mendeleev Commun. 34 (3), 351-353. https://doi.org/10.1016/j.mencom.2024.04.013.
[12] Egorova, K.S., Posvyatenko, A.V., Galushko, A.S., Kolesnikov, A.E., 2024. Assessing the contribution of reaction components to the overall toxicity of synthesis of 4-methoxy-4'-nitro-1,1'-biphenyl. Mendeleev Commun. 34 (2), 181-184. https://doi.org/10.1016/j.mencom.2024.02.007.
[13] Kolesnikov, A.E., Egorova, K.S., 2024. Evaluation of toxicity of ionic liquids as solvents in C–C cross-coupling reaction. Doklady Chem. 514 (2), 50-57. https://doi.org/10.1134/s0012500824600068.
[14] Tolstikov, S., Smirnova, K., Kolesnikov, A., Letyagin, G., Bogomyakov, A., Romanenko, G., Ovcharenko, V., 2023. Relationship between phase transition temperature and accessible volume for substituent in Cu(hfac)2 chain-polymer complexes with pyridine-based nitroxides. Polyhedron 230, 116212. https://doi.org/10.1016/j.poly.2022.116212.
[15] Prima, D.O., Makarov, A.G., Bagryanskaya, I.Y., Kolesnikov, A.E., Zargarova, L.V., Baev, D.S., Eliseeva, T.F., Politanskaya, L.V., Makarov, A.Y., Slizhov, Y.G., Zibarev, A.V., 2019. Fluorine?containing n?6?and angular and linear n?6?n' (n, n' = 5, 6, 7) diaza?heterocyclic scaffolds assembled on benzene core in unified way. ChemistrySelect 4 (8), 2383-2386. https://doi.org/10.1002/slct.201803970.
Хобби:
Путешествия, межкультурная коммуникация, изучение новых языков.
