07 February 2017

IOLIOMICS is defined as a rapidly emerging research discipline dealing with the studies of ions in liquid phases and revealing fundamental properties of ionic interactions in biological and chemical systems (doi: 10.1021/acs.chemrev.6b00562).

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23 May 2016

Metal oxides represent primary source of catalytic materials for a variety of industrial and research applications, either as an active phase or as a supporting phase. Mechanistic study conducted by Ananikov group revealed formation of catalytically active species due to partial dissolution of metal oxide in the reaction mixture and generation of soluble metal complexes.

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25 February 2016

In this review, the possible versatile synthons suitable for preparation of the main types of organic compounds using molecular 3D printing are examined. The surveyed data strongly indicate that alkyne molecules may be used as a building material in a molecular 3D printer working on hydrocarbons.

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08 February 2016

A new joint theoretical and experimental study suggests that graphene sheets efficiently shield chemical interactions. One of the promising applications of this phenomenon is associated with improving the quality of 2D materials by "de-charging" defect centers on the surfaces of carbon materials. Another important feature is the ability to control selectivity and activity of the supported metallic catalysts M/C on the carbon substrate.

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11 January 2016

A group of researchers from Zelinsky Institute have addressed technical questions concerning routine analytic characterization and provided a concise description of the most important features regarding the accuracy and sensitivity of NMR, EI-MS and ESI-MS measurements.

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17 December 2015

Researchers led by Prof. Ananikov highlighted that Ni-NHC complexes do undergo a hydrolysis with a breakage of metal-ligand bond.

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17 December 2015

The present study conducted by a high school student Gleb Rukhovich under supervision of PhD student Leonid Romashov shows that contact with water facilitates simple platinum and palladium salts to aggregate into various clusters - chemical species, which contain more than one metal atom. It is an important observation, since toxicity of clusters can significantly exceed toxicity of simple salts.

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13 November 2015

A unique palladium catalyst was developed in the laboratory of Prof. Ananikov at the Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences.

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12 November 2015

The human body is composed of numerous types of molecules, both simple and complex, and all fundamental processes in a living body occur in water solutions. Therefore, for a drug to work, it must dissolve in body liquids, which are primarily water. Polymorphism of solid substances, a well-known problem of drug delivery, is the ability of solid drugs to form several different crystal structures (polymorphs). Polymorphs may differ in properties like biological activity, and in addition, their formation is difficult to control.

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10 November 2015

A recently published study gives a vivid example of unusual chemical reactivity associated with organogold complexes. Using modern physical methods and computational studies, the authors propose a reaction mechanism in which a molecule of acetic acid serves as a proton shuttle, transferring the hydrogen atom between the reaction centers.

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09 October 2015

Researchers of the laboratory compared three different drug delivery models based on ionic liquids. Scientists have developed a powerful API-IL concept to realize structural diversity and to develop dual-action pharmaceuticals. The study, published in ACS Medicinal Chemistry Letters, introduces new drug delivery concepts using ionic and covalent molecular interactions.

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12 August 2015

Research work was carried out within the framework of the Russian Science Foundation and studied application of graphene materials in chemical reactions.


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12 August 2015

A joint project of scientists from Russia has investigated chemical applications of calcium carbide. The project advances the idea of diverse acetylene chemistry on the basis of carbide technology. Using the proposed approach, cheap, available raw carbide material has been effectively transformed into valuable products that are in demand for material science and organic synthesis.

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24 July 2015

A recently published study gives a vivid example of unusual chemical reactivity associated with organogold complexes. Using modern physical methods and computational studies, the authors propose a reaction mechanism in which a molecule of acetic acid serves as a proton shuttle, transferring the hydrogen atom between the reaction centers.


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07 July 2015

ZIOC installed a 3D printer in the laboratory of professor Ananikov on July 6, 2015. 3D printing technology will be used in breakthrough projects, aimed at developing efficient chemical reactors and microreactor systems.


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15 June 2015

Increasing demand from high technology sectors for better approaches to industrial production is prompting the emergence of a new generation of chemical synthesis methods.

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20 May 2015

A convenient procedure to visualize defects on graphene layers by mapping the surface of carbon materials with an appropriate contrast agent was introduced by a team of researchers from Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences (Moscow) involved in international collaborative project. A new imaging tomography procedure has revealed organized patterns of defects on large areas of carbon surfaces. Several types of defects on the carbon surface can be "caught" and captured on the microscopic image within a few minutes. The article describing the research was published in Chemical Science, the journal of the Royal Society of Chemistry.


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09 April 2015

A computational study carried out at Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences (Moscow) focused on the mechanistic pathway of the enzyme-catalyzed cycloaddition reaction leading to Spinosyn A – tetracyclic natural insecticide produced by the cells of the bacterium Saccharopolyspora spinosa. Computational modeling revealed energetically balanced reaction coordinate of the studied process and highlighted new possibilities for the enzymatic catalysis of cycloaddition reactions. The study was published in PLOS ONE journal.


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08 April 2015

Replacement of toxic chemical components by nontoxic and biocompatible natural analogs is one of the most popular approaches in sustainable projects. A study carried out at Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences (Moscow) has shown that partial replacement of chemical compounds by their natural analogs may surprisingly lead to even more toxic products. The article published in Toxicology Research describes increased toxicity of ionic liquids after incorporation of amino acid residues.


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05 March 2015

Chemical science is in need to replace more and more expansive metal catalysts with easier accessible alternatives. Finding an opportunity to employ non-precious metals for chemicals production would solve the problem and will ensure sustainable future.

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17 February 2015

A superatom is a combination of two or more atoms that form a stable structural fragment and possess unique physical and chemical properties. Systems that contain superatoms open a number of possibilities for not only formation of new materials, but also for revealing unusual chemical reactivity. Throughout a given chemical transformation process, a superatom acts as a single unit and is left unchanged during the reaction. As a result, it would be logical to consider superatoms as elements of the periodic table in a nanoscale world. Potential areas of application for superatoms are quite broad – currently, many research directions are being explored worldwide in catalysis, material sciences, organometallic chemistry, and medical research.

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13 December 2014

Research of the laboratory showed that grain boundaries of graphene layers are supposed to modulate chemical interactions on carbon material surfaces. This phenomenon reveals promising prospects of applications of carbon materials' nano-sized effects in organic chemistry and catalysis.

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02 December 2014

Graphene "cut and paste" with metal nanoparticles was carried out under microwave irradiation. The study revealed unique processes occurring on the carbon layers under the influence of metal nanoparticles heated by microwave irradiation. Understanding the processes taking place in Metal/Carbon systems is crucial for development of new generation of highly efficient catalysts for organic synthesis and chemical industry. The authors described the key transformations responsible for catalyst evolution in connection with preparation of nanostructured Metal/Carbon systems.

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